POS1464-HPR ASSESSMENT OF EMOTIONAL WELL-BEING IN RHEUMATIC PATIENTS DURING COVID-19 LOCKDOWN THROUGH A WEB-BASED SURVEY APPROACH

Background: The severe measures of lockdown imposed in Italy to limit the SARS coronavirus 2 disease (COVID-19) spread caused an increase reported anxiety, depression and suicidal rate among general population. Patients affected by rheumatic disorders feature increased risk mood for chronic course itself related disability. Objectives: Aim this study was investigate impact COVID-19 on emotional well-being a large cohort patients through telemedicine approach. Methods: follow-up rheumatologic out-patient clinics our hospital were invited participate online survey. They asked also invite their best friend, matched age sex, survey, as control group. survey included demographic questions validated, psychometric scales stress vulnerability (Stress Vulnerability Scale-SVS), resilience (Resilience Scale-RS), (Zung’s questionnaire-Zung-D) anxiety questionnaire-Zung-A) evaluation. Results: composed 484 subjects (84,1% F, 15,9% M). number frequency various diagnosis are shown Table 1. According scales, 55,5% 43,3% subject showed respectively reduced resiliency. Moreover, 64% 40,5% enrolled depressive symptoms worthy psychiatric attention. There significant different distribution scores SVS (p<0,0001), Zung-A (p<0,0001) Zung-D diagnosis. In comparison with controls, higher present connective tissue diseases (CTD) (p=0,007), Sjogren’s Syndrome (SSJ) (p=0,0029) fibromyalgia (FM) patients, SSJ (p=0,006) FM (Figure 1). Ordinal regression analysis that classes independently predicted Tension (β=0,32;CI=0,13-0,52;p=0,003) Demoralization (β=0,22;CI=0,04-0,44;p=0,046) components score (β=0,09;CI=0,05-0,1;p<0,001), while total (β=0,17;CI=0,03-0,30;p=0,012), its subcomponent (β=0,22;CI=0,01-0,43;p=0,038), lower absolute RS (β=-0,083;CI=-0,1--0,06;p<0,001) (β=0,11;CI=0,06-0,15;p<0,001). both cases, specific not associated advanced classes. Conclusion: Rheumatic developed high following lockdown, which part should be referred specialist attention according severity. variability CTD, most susceptible development vulnerability. application psycometric approach represents useful tool identify levels depression. DIAGNOSIS Frequency Percent Controls 45 9,3 RA 82 16,9 PSA 21 4,3 UA 4 0,8 SPA 7 1,4 CTD 70 14,5 79 16,3 Myositis 8 1,7 Behcet’s 11 2,3 Vasculitis 16 3,3 APS 6 1,2 Other AID 13 2,7 122 25,2 Total 100 RA: Rheumatoid Arthritis, PSA: Psoriatic Arthritis; UA: Undifferentiated SPA: Spondyloarthritis; CTD: Connective tissues (including Systemic Lupus Erythematosus, Scleroderma, Connettivitis, Mixed Connettivitis); FM: Fibromyalgia; APS: Anti-phospholipid syndrome; AID: autoimmune/inflammatory Adult-onset Still disease, IgG4 disease); SSJ: Sjogren Figure Disclosure Interests: None declared